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Did UCLA Just Cure Baldness?

Did UCLA Just Cure Baldness?

38 comments

·February 7, 2025

nico

Looks like they might be close to a generally available treatment. It says they've had successful human trials and they are expanding them

Also:

> the scientists have co-founded a medical development company called Pelage Pharmaceuticals. Backed by Google Ventures, last year the company raised $16.4 million in funding to shepherd further trials and win official clearances

Traubenfuchs

The majority of men can fully stop hair loss with oral finasteride.

Some need the stronger dutasteride for it.

Both medications are known to stop and even revert hair loss, but the real regrowth usually happens if you additionally take oral minoxidil.

I am on dut+min for years now.

Neither of those three is without side effects though and they can‘t revive „truly dead“ follicles, so this is great news.

chakintosh

> The majority of men can fully stop hair loss with oral finasteride.

I did that, and it completely ruined my libido for almost 3 years. Never again.

baldieburner

Same. I took finasteride (propecia) for a week and it caused ED for 60 days in my early 20s when libido was usually strong. Would not recommend finasteride. Hair did grow back thick, but it was not worth it. Scariest 60 days of my life. Also felt strange because I think it reduces testosterone; I felt more easily upset and different to usual. Difficult to describe and I'm no expert. I was suddenly very happy to be bald, as the finasteride alternative was far worse and a scary experience.

zdc1

I've been taking 1mg orally for 2-3 years with noticeable side effects

seanthemon

Would love to hear the side effects, i'm balding and was considering this or just going full chop

whitfin

I just tried this in the last few weeks after oral minoxidil didn't do anything noteworthy; I was on it for only a week before I started having these bizarre and extremely vivid/realistic dreams.

I'd never read about that as a side effect so at first I didn't connect the dots, but it was almost daily. Stopped after I stopped taking it - I looked it up out of interest and it's a rare side effect. I wasn't keen on it because it was a neurological side effect.

The dreams themselves didn't bother me but I also found myself more tired than usual, and I'm not overly bothered about my hair so dropped it. Others will probably tell you about the more common side effects, but wanted to drop this one in as it's not often mentioned!

DrBenCarson

No libido, erectile dysfunction, testicular pain, depression and suicidal ideation

You’re basically eliminating the most potent testosterone analog in your body because it can also damage hair follicles

Everyone’s different, but I was not willing to trade my manhood for my hair

UberFly

Go full chop and live like you don't care (which you shouldn't).

littlecranky67

Other opinion here: Women really find hair attractive, and without it you will have harder time dating. Lot of bald man compensate this somehow (career,gym, etc.).

Springtime

From what I've read finasteride can cause general psychological adverse events, including suicidal ideation[1], in mostly younger people. Heard someone saying their suicidal thoughts began when taking it and stopped when not, leading them to find more info about it.

[1] https://pubmed.ncbi.nlm.nih.gov/33175100/

raffraffraff

Also loss of libido, erectile dysfunction. It's a gas. Imagine being 60 years old, working out, doing Botox, taking finasteride, looking great, attracting glances from women 20 years younger. Can't get it up and keep thinking about killing oneself.

It's a deal

cyberax

Oral low-dose minoxidil doesn't seem to have much in the way of side effects once you get used to it. It even can be mildly cardio protective. Very rare side effects include pericarditis that goes away if minoxidil is discounted.

Finasteride is more hit-or-miss.

pstuart

Hopefully this works for those of us who do experience side effects from finasteride.

arrowsmith

Why bother? I don't really care about going bald.

If baldness was as unattractive to women as many men think it is, male pattern baldness wouldn't have evolved.

DamnYuppie

I am not sure that makes sense, historically people were marrying and having children much younger. I am talking about under 20 years of age. As such I don't think it would have much impact on mate selection as it was done when they were younger and had more "follicle vibrancy".

CalRobert

It usually sets in past your prime years though. Maybe it was an advantage on a societal level to make men less attractive in middle age compared to young men.

(I say this as a 42 year old who misses my hair)

otikik

Evolution only “cares” (it doesn’t care; you know what I mean) about attractiveness during the time the male is able to procreate. Which is, <= 30 years. After that, the human animal is dead of sickness, malnutrition or a fight. The human person lives way longer thanks to modern medicine and tech. Evolution might “cares” about the male sticking around defending/teaching the family/tribe until he dies. He doesn’t need to be attractive by that point.

cosmic_cheese

I think it depends a lot on factors like head size/shape, proportionality to the rest of the body, etc. Some guys look amazing bald, but having been almost bald (very close cut) I find it quite awkward looking on myself.

tempestn

Unless most procreation was done before it developed.

root_axis

Not necessarily true. It could be that MPB evolved because it allowed females to select for younger males.

null

[deleted]

apeescape

Many people do care about it though, just see the market size of hair implants and Rogaine.

barrenko

> men care.

plun9

Does Betteridge’s law of headlines apply here?

eru

Does Betteridge’s law of comments apply here?

BMc2020

What good are luxurious locks if they surround a 50 year old face?

(do an image search for a guy named phil spector)

apeescape

Many people balden in their 20s or 30s.

tempestn

Thick hair looks great on older men. See some of these for instance: https://onpointfresh.com/the-best-hairstyles-for-older-men/

djmips

Those are wigs.

XorNot

The silver fox look totally works for men.

eggsandbeer

Yeah, but imagine how bad he'd look bald.

tehjoker

wear sunscreen :)

bigmattystyles

I guess it's all a matter of perspective but having suffered from some very mild pain and lifelong depression and OCD, I would trade my thick ass 43-year old beautiful blond locks for some baldness if I could. My point, and I know I have no right to, but when I see all these otherwise super healthy men spend so much time worried about their (lack of) hair, it's hard to sympathize. But hey, everyone has a cross to bear I suppose.